2xx8: Difference between revisions

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[[Image:2xx8.png|left|200px]]
[[Image:2xx8.png|left|200px]]


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{{STRUCTURE_2xx8|  PDB=2xx8  |  SCENE=  }}  
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===CRYSTAL STRUCTURE OF N,N-DIMETHYL-4-(3-(TRIFLUOROMETHYL)-4, 5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.===
===CRYSTAL STRUCTURE OF N,N-DIMETHYL-4-(3-(TRIFLUOROMETHYL)-4, 5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.===


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==See Also==
==See Also==
*[[Ionotropic Glutamate Receptors]]
*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]


==Reference==
==Reference==

Revision as of 21:32, 25 July 2012

File:2xx8.png

Template:STRUCTURE 2xx8

CRYSTAL STRUCTURE OF N,N-DIMETHYL-4-(3-(TRIFLUOROMETHYL)-4, 5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.

Template:ABSTRACT PUBMED 21128618

About this Structure

2xx8 is a 3 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators. J Med Chem. 2010 Dec 3. PMID:21128618 doi:10.1021/jm100679e

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