3tza: Difference between revisions
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===Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution=== | |||
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{{ABSTRACT_PUBMED_21923187}} | |||
==About this Structure== | |||
[[3tza]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus,_synthetic,_rattus_norvegicus Rattus norvegicus, synthetic, rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021923187</ref><references group="xtra"/> | |||
[[Category: Rattus norvegicus, synthetic, rattus norvegicus]] | |||
[[Category: Frydenvang, K.]] | |||
[[Category: Kastrup, J S.]] | |||
[[Category: Ampa receptor ligand-binding domain]] | |||
[[Category: Antagonist]] | |||
[[Category: Glua2-s1s2j]] | |||
[[Category: Membrane protein]] | |||
Revision as of 09:27, 30 October 2011
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid at 1.9A resolution
Template:ABSTRACT PUBMED 21923187
About this Structure
3tza is a 2 chain structure with sequence from Rattus norvegicus, synthetic, rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Szymanska E, Frydenvang K, Contreras-Sanz A, Pickering DS, Frola E, Serafimoska Z, Nielsen B, Kastrup JS, Johansen TN. A New Phenylalanine Derivative Acts as an Antagonist at the AMPA Receptor GluA2 and Introduces Partial Domain Closure: Synthesis, Resolution, Pharmacology, and Crystal Structure. J Med Chem. 2011 Oct 27;54(20):7289-98. Epub 2011 Oct 4. PMID:21923187 doi:10.1021/jm200862h
