1mem: Difference between revisions

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Line 14: Line 14:
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Mcgrath, M.E.]]
[[Category: Mcgrath, M E.]]
[[Category: BNS]]
[[Category: BNS]]
[[Category: BZP]]
[[Category: BZP]]
Line 24: Line 24:
[[Category: protease]]
[[Category: protease]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:53:31 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:54:27 2008''

Revision as of 11:54, 21 February 2008

File:1mem.gif


1mem, resolution 1.8Å

Drag the structure with the mouse to rotate

CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR

Disease

Known disease associated with this structure: Pycnodysostosis OMIM:[601105]

About this Structure

1MEM is a Single protein structure of sequence from Homo sapiens with BZP and BNS as ligands. Active as Cathepsin K, with EC number 3.4.22.38 Known structural/functional Site: CAT. Full crystallographic information is available from OCA.

Reference

Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587

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