1ocn: Difference between revisions
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==Overview== | ==Overview== | ||
A cellobio-derived isofagomine glycosidase inhibitor (Ki approximately 400 | A cellobio-derived isofagomine glycosidase inhibitor (Ki approximately 400 nM) displays an unusual distorted 2,5B (boat) conformation upon binding to cellobiohydrolase Cel6A from Humicola insolens, highlighting the different conformational itineraries used by various glycosidases, with consequences for the design of therapeutic agents. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Humicola insolens]] | [[Category: Humicola insolens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Davies, G | [[Category: Davies, G J.]] | ||
[[Category: Gilbert, H | [[Category: Gilbert, H J.]] | ||
[[Category: Macdonald, J.]] | [[Category: Macdonald, J.]] | ||
[[Category: Pell, G.]] | [[Category: Pell, G.]] | ||
[[Category: Stick, R | [[Category: Stick, R V.]] | ||
[[Category: Varrot, A.]] | [[Category: Varrot, A.]] | ||
[[Category: BGC]] | [[Category: BGC]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:16:05 2008'' | ||
