4a55: Difference between revisions
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===Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108=== | |||
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{{ABSTRACT_PUBMED_22120714}} | |||
==About this Structure== | |||
[[4a55]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A55 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022120714</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Mus musculus]] | |||
[[Category: Berndt, A.]] | |||
[[Category: Hon, W C.]] | |||
[[Category: Williams, R L.]] | |||
[[Category: Cancer mutation]] | |||
[[Category: Enzyme regulation]] | |||
[[Category: Growth factor signalling]] | |||
[[Category: Lipid kinase]] | |||
[[Category: Membrane binding]] | |||
[[Category: Non-atp competitive ligand binding site]] | |||
[[Category: Oncogene]] | |||
[[Category: Pi3-kinase inhibitor]] | |||
[[Category: Structure-activity relationship]] | |||
[[Category: Transferase]] | |||
[[Category: Tumour]] | |||
Revision as of 07:23, 28 December 2011
Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108
Template:ABSTRACT PUBMED 22120714
About this Structure
4a55 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Hon WC, Berndt A, Williams RL. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.532. PMID:22120714 doi:10.1038/onc.2011.532
