3pnf: Difference between revisions

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[[Image:3pnf.jpg|left|200px]]
[[Image:3pnf.png|left|200px]]


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{{STRUCTURE_3pnf|  PDB=3pnf  |  SCENE=  }}  
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===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((2,2-Difluoro-2-(2-chlorophenyl)ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine===
===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((2,2-Difluoro-2-(2-chlorophenyl)ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine===


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{{ABSTRACT_PUBMED_21809851}}
{{ABSTRACT_PUBMED_21809851}}


==About this Structure==
==About this Structure==
[[3pnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNF OCA].  
[[3pnf]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNF OCA].  
 
==See Also==
*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]


==Reference==
==Reference==

Revision as of 15:26, 26 July 2012

File:3pnf.png

Template:STRUCTURE 3pnf

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((2,2-Difluoro-2-(2-chlorophenyl)ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

Template:ABSTRACT PUBMED 21809851

About this Structure

3pnf is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Xue F, Kraus JM, Labby KJ, Ji H, Mataka J, Xia G, Li H, Delker SL, Roman LJ, Martasek P, Poulos TL, Silverman RB. Improved Synthesis of Chiral Pyrrolidine Inhibitors and Their Binding Properties to Neuronal Nitric Oxide Synthase. J Med Chem. 2011 Sep 22;54(18):6399-6403. Epub 2011 Aug 22. PMID:21809851 doi:10.1021/jm200411j

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