3tge: Difference between revisions
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[[Image:3tge. | [[Image:3tge.png|left|200px]] | ||
{{STRUCTURE_3tge| PDB=3tge | SCENE= }} | {{STRUCTURE_3tge| PDB=3tge | SCENE= }} | ||
===A novel series of potent and selective PDE5 inhibitor1=== | ===A novel series of potent and selective PDE5 inhibitor1=== | ||
{{ABSTRACT_PUBMED_21955943}} | {{ABSTRACT_PUBMED_21955943}} | ||
==About this Structure== | ==About this Structure== | ||
[[3tge]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGE OCA]. | [[3tge]] is a 1 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGE OCA]. | ||
==See Also== | |||
*[[Phosphodiesterase|Phosphodiesterase]] | |||
==Reference== | ==Reference== | ||
Revision as of 20:10, 25 July 2012
A novel series of potent and selective PDE5 inhibitor1
Template:ABSTRACT PUBMED 21955943
About this Structure
3tge is a 1 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hughes RO, Maddux T, Joseph Rogier D, Lu S, Walker JK, Jon Jacobsen E, Rumsey JM, Zheng Y, Macinnes A, Bond BR, Han S. Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6348-52. Epub 2011 Aug 31. PMID:21955943 doi:10.1016/j.bmcl.2011.08.106