Sandbox 39: Difference between revisions
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Papain is also known to cleave antibodies above and below the disulfide bonds that join the heavy chains and that is found between the light chain and heavy chain. This generates two monovalent Fab segments, that each have a single antibody binding sites, and an intact Fc fragment, as shown below: | Papain is also known to cleave antibodies above and below the disulfide bonds that join the heavy chains and that is found between the light chain and heavy chain. This generates two monovalent Fab segments, that each have a single antibody binding sites, and an intact Fc fragment, as shown below: | ||
[[Image:2fab_fc.png|left | [[Image:2fab_fc.png|left]] | ||
<ref>Image from: | <ref>Image from: | ||
http://en.wikipedia.org/wiki/Papain</ref>]] | http://en.wikipedia.org/wiki/Papain</ref>]] | ||
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<Structure load='9pap' size='300' frame='true' align='left' caption='Ribbon Structure of Papain' scene=/> | <Structure load='9pap' size='300' frame='true' align='left' caption='Ribbon Structure of Papain' scene=/> | ||
