1knk: Difference between revisions

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[[Image:1knk.png|left|200px]]
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===Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis===
===Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis===
{{ABSTRACT_PUBMED_11786530}}


==Function==
[[http://www.uniprot.org/uniprot/ISPF_ECOLI ISPF_ECOLI]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). Also converts 4-diphosphocytidyl-2-C-methyl-D-erythritol into 2-C-methyl-D-erythritol 3,4-cyclophosphate and CMP.<ref>PMID:10694574</ref> <ref>PMID:22839733</ref> 


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==About this Structure==
The line below this paragraph, {{ABSTRACT_PUBMED_11786530}}, adds the Publication Abstract to the page
[[1knk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNK OCA].
(as it appears on PubMed at http://www.pubmed.gov), where 11786530 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11786530}}


==About this Structure==
==See Also==
[[1knk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNK OCA].
*[[MECDP synthase|MECDP synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:011786530</ref><references group="xtra"/>
<ref group="xtra">PMID:011786530</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Bacillus coli migula 1895]]
[[Category: Bowman, M E.]]
[[Category: Bowman, M E.]]
[[Category: Cane, D E.]]
[[Category: Cane, D E.]]