1knk: Difference between revisions
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{{STRUCTURE_1knk| PDB=1knk | SCENE= }} | {{STRUCTURE_1knk| PDB=1knk | SCENE= }} | ||
===Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis=== | ===Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis=== | ||
{{ABSTRACT_PUBMED_11786530}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ISPF_ECOLI ISPF_ECOLI]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). Also converts 4-diphosphocytidyl-2-C-methyl-D-erythritol into 2-C-methyl-D-erythritol 3,4-cyclophosphate and CMP.<ref>PMID:10694574</ref> <ref>PMID:22839733</ref> | |||
==About this Structure== | |||
[[1knk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNK OCA]. | |||
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== | ==See Also== | ||
[[ | *[[MECDP synthase|MECDP synthase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011786530</ref><references group="xtra"/> | <ref group="xtra">PMID:011786530</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Bacillus coli migula 1895]] | ||
[[Category: Bowman, M E.]] | [[Category: Bowman, M E.]] | ||
[[Category: Cane, D E.]] | [[Category: Cane, D E.]] | ||