Tom Sandbox: Difference between revisions
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===Hydrophobic Stability=== | ===Hydrophobic Stability=== | ||
GCN4 is composed of two identical 58 residue alpha helix chains that grouped together to form a parallel coiled-coil dimer. Roughly 33 of the 58 total residues are located in the Leucine Zipper region. The dimer binds through interlocking leucine amino acids and <scene name='Tom_Sandbox/Hydrophobic_and_philic_regions/3'>hydrophobic residues</scene> near the C terminus, while pinching in on the major groove of DNA in the N terminal end via basic residues. | GCN4 is composed of two identical 58 residue alpha helix chains that grouped together to form a parallel coiled-coil dimer. Roughly 33 of the 58 total residues are located in the Leucine Zipper region. The dimer binds through interlocking leucine amino acids and <scene name='Tom_Sandbox/Hydrophobic_and_philic_regions/3'>hydrophobic residues</scene> near the C terminus, while pinching in on the major groove of DNA in the N terminal end via basic residues. The aforementioned image shows how the hydrophobic regions are between the helices, while the hydrophobic regions protrude outwards. | ||
{{STRUCTURE_1ysa| PDB=1ysa | SCENE= }} | {{STRUCTURE_1ysa| PDB=1ysa | SCENE= }} | ||
===Zipper and Binding Domains=== | ===Zipper and Binding Domains=== | ||
