Sandbox Reserved 382: Difference between revisions
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== Function == | == Function == | ||
The primary function of Aromatase is to produce estrogens by aromatizing androgens. Aromatase converts androstenedione to estrogen and testosterone to estradiol. <ref> "Aromatase Products" [http://www.novusbio.com/aromatase#13225047480835&ga_enabled%3B0] </ref> Aromatase is also a key enzyme in the biosynthesis of estrogens through a process called steroidogenesis. This enzyme helps produce this female sex hormone, estrogen, that helps to fuel the growth of hormone receptor-positive breast cancer. | The primary function of Aromatase is to produce estrogens by aromatizing androgens. Aromatase converts androstenedione to estrogen and testosterone to estradiol. <ref> "Aromatase Products" [http://www.novusbio.com/aromatase#13225047480835&ga_enabled%3B0] </ref> Aromatase is also a key enzyme in the biosynthesis of estrogens through a process called steroidogenesis. This enzyme helps produce this female sex hormone, estrogen, that helps to fuel the growth of hormone receptor-positive breast cancer. | ||
[[Image:Aromatase_Structure.jpg|260px|left|'The ribbon diagram displaying the overall structure of human placental aromatase'|]] | [[Image:Aromatase_Structure.jpg|260px|left|'The ribbon diagram displaying the overall structure of human placental aromatase'| <ref>Ghosh,D., Griswold,J., Erman,M., Pangborn, W. "X-ray Structure of Human Aromatase Reveals Androgen-Specific Active Site." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826573/] </ref>]] | ||
== Structure== | == Structure== | ||
