Sandbox Reserved 382: Difference between revisions
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== Function == | == Function == | ||
The primary function of Aromatase is to produce estrogens by aromatizing androgens. Aromatase converts androstenedione to estrogen and testosterone to estradiol. <ref | The primary function of Aromatase is to produce estrogens by aromatizing androgens. Aromatase converts androstenedione to estrogen and testosterone to estradiol. <ref name="products" /> Aromatase is also a key enzyme in the biosynthesis of estrogens through a process called steroidogenesis. This enzyme helps produce this female sex hormone, estrogen, that helps to fuel the growth of hormone receptor-positive breast cancer. | ||
[[Image:Aromatase_Structure.jpg|thumb|260px|left|Ribbon diagram displaying the overall structure of human placental aromatase| <ref name="structure">Ghosh,D., Griswold,J., Erman,M., Pangborn, W. "X-ray Structure of Human Aromatase Reveals Androgen-Specific Active Site." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826573/] </ref>]] | [[Image:Aromatase_Structure.jpg|thumb|260px|left|Ribbon diagram displaying the overall structure of human placental aromatase| <ref name="structure">Ghosh,D., Griswold,J., Erman,M., Pangborn, W. "X-ray Structure of Human Aromatase Reveals Androgen-Specific Active Site." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826573/] </ref>]] | ||
