3uai: Difference between revisions

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~~[[Image:3uai.jpg|left|200px]]~~

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===Structure of the Shq1-Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae===

==Function==

<~~!--~~

[[http://www.uniprot.org/uniprot/SHQ1_YEAST SHQ1_YEAST]] Involved in the early biogenesis steps of box H/ACA snoRNP assembly.<ref>PMID:12228251</ref> [[http://www.uniprot.org/uniprot/CBF5_YEAST CBF5_YEAST]] Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. May function as a pseudouridine synthase. Binds in vitro to centromeres and microtubules. It is a centromeric DNA-CBF3-binding factor which is involved in mitotic chromosome segregation. Essential for cell growth.<ref>PMID:8336724</ref> <ref>PMID:9315678</ref> <ref>PMID:9472021</ref> <ref>PMID:9848653</ref> <ref>PMID:10523634</ref> [[http://www.uniprot.org/uniprot/GAR1_YEAST GAR1_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9303321</ref> [[http://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>

~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_22117216}}~~, ~~adds~~ the ~~Publication Abstract~~ to the ~~page~~

(as ~~it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~), ~~where 22117216 is~~ the ~~PubMed ID number~~.

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~~{{ABSTRACT_PUBMED_22117216}}~~

==About this Structure==

[[3uai]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae~~ Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAI OCA].

[[3uai]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAI OCA].

==Reference==

[[Category: Saccharomyces cerevisiae]]

[[Category: Saccharomyces cerevisiae s288c]]

[[Category: Ye, K.]]

[[Category: H/aca rna]]

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-[[Image:3uai.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3uai", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3uai|  PDB=3uai  |  SCENE=  }}
 ===Structure of the Shq1-Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae===
+{{ABSTRACT_PUBMED_22117216}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/SHQ1_YEAST SHQ1_YEAST]] Involved in the early biogenesis steps of box H/ACA snoRNP assembly.<ref>PMID:12228251</ref>  [[http://www.uniprot.org/uniprot/CBF5_YEAST CBF5_YEAST]] Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. May function as a pseudouridine synthase. Binds in vitro to centromeres and microtubules. It is a centromeric DNA-CBF3-binding factor which is involved in mitotic chromosome segregation. Essential for cell growth.<ref>PMID:8336724</ref> <ref>PMID:9315678</ref> <ref>PMID:9472021</ref> <ref>PMID:9848653</ref> <ref>PMID:10523634</ref>  [[http://www.uniprot.org/uniprot/GAR1_YEAST GAR1_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9303321</ref>  [[http://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
-The line below this paragraph, {{ABSTRACT_PUBMED_22117216}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 22117216 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_22117216}}
 ==About this Structure==
-[[3uai]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAI OCA].
+[[3uai]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAI OCA].
 ==Reference==
-<ref group="xtra">PMID:022117216</ref><references group="xtra"/>
+<ref group="xtra">PMID:022117216</ref><references group="xtra"/><references/>
-[[Category: Saccharomyces cerevisiae]]
+[[Category: Saccharomyces cerevisiae s288c]]
 [[Category: Ye, K.]]
 [[Category: H/aca rna]]