Sandbox 27: Difference between revisions
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<Structure load='3g04' size='500' frame='true' align='right' caption='M22 autoantibody complexed with TSHR' scene='Insert optional scene name here' | left /> | <Structure load='3g04' size='500' frame='true' align='right' caption='M22 autoantibody complexed with TSHR' scene='Insert optional scene name here' | left /> | ||
M22 binds to the concave surface of the LRD domain | M22 binds to the concave surface of the LRD domain (residues 1 to 260 of TSHR) | ||
The binding results of several interactions between TSHR and M22, most of them are hydrogen bonds and salt bridges. The <scene name='Sandbox_27/Chaine_b/3'>heavy chain</scene> (HC, or Chain B) of M22 has more interactions with the <scene name='Sandbox_27/Chaine_c/1'>LRD</scene> than has the <scene name='Sandbox_27/Chaine_a/2'>light chain</scene> (LC, or Chain A), respectively 14 and 8 interactions. [http://www.hotthyroidology.com/editorial_175.htm] | The binding results of several interactions between TSHR and M22, most of them are hydrogen bonds and salt bridges. The <scene name='Sandbox_27/Chaine_b/3'>heavy chain</scene> (HC, or Chain B) of M22 has more interactions with the <scene name='Sandbox_27/Chaine_c/1'>LRD</scene> than has the <scene name='Sandbox_27/Chaine_a/2'>light chain</scene> (LC, or Chain A), respectively 14 and 8 interactions. [http://www.hotthyroidology.com/editorial_175.htm] | ||
