Sandbox 212: Difference between revisions
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Carnitine acyltransferases include three different classes of enzymes which are known as carnitine acetyltransferases (CrATs), carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). The three classes of differ in their acyl group specificity as well as their localization.<ref> | Carnitine acyltransferases include three different classes of enzymes which are known as carnitine acetyltransferases (CrATs), carnitine octanoyltransferases (CrOTs) and carnitine palmityltransferase (CPTs). The three classes of differ in their acyl group specificity as well as their localization.<ref> | ||
Being major enzymes in fatty acid oxidation carnitine acyltransferases are viewed as promising targets which can be used to develop successful therapeutics against type 2 diabetes, obesity and other human diseases. | Being major enzymes in fatty acid oxidation carnitine acyltransferases are viewed as promising targets which can be used to develop successful therapeutics against type 2 diabetes, obesity and other human diseases. | ||
== Biological function == | == Biological function == | ||
[[Image:Second step.jpg|thumb|second step of the carnitine shuttle|600px|right]] | |||
[[Image:Second step.jpg|thumb|second step of the carnitine shuttle|600px|right]] | [[Image:Second step.jpg|thumb|second step of the carnitine shuttle|600px|right]] | ||
