Sandbox 215: Difference between revisions
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* At each end of the protein there is a barrel which is constitued of highly twisted B-sheet and two helices called A and B at the N-terminal and A', B' at C-terminal extremity. Helices B and B' are longer than A and A' | * At each end of the protein there is a barrel which is constitued of highly twisted B-sheet and two helices called A and B at the N-terminal and A', B' at C-terminal extremity. Helices B and B' are longer than A and A' | ||
* Between the two barrels there is a central B-sheet which is constitued of six antiparallel strands | * Between the two barrels there is a central B-sheet which is constitued of six antiparallel strands | ||
* At the C-terminal extremity there is a distorted amphiphathic helix called helix X which is an extension of C-teminal and she interacts with N-terminal residues | * At the C-terminal extremity there is a distorted amphiphathic helix called helix X which is an extension of C-teminal and she interacts with N-terminal residues. | ||
===Four lipid binding sites=== | |||
==CETP inhibition== | ==CETP inhibition== | ||
