2j3p: Difference between revisions

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==Overview==

Fibroblast growth factors (FGFs) constitute a family of 22 structurally, related heparin-binding polypeptides that are involved in the regulation, of cell growth, survival, differentiation and migration. Here, a 1.4 A, resolution X-ray structure of rat FGF1 is presented. Two molecules are, present in the asymmetric unit of the crystal and they coordinate a total, of five sulfate ions. The structures of human, bovine and newt FGF1 have, been published previously. Human and rat FGF1 are found to have very, similar structures.

Fibroblast growth factors (FGFs) constitute a family of 22 structurally related heparin-binding polypeptides that are involved in the regulation of cell growth, survival, differentiation and migration. Here, a 1.4 A resolution X-ray structure of rat FGF1 is presented. Two molecules are present in the asymmetric unit of the crystal and they coordinate a total of five sulfate ions. The structures of human, bovine and newt FGF1 have been published previously. Human and rat FGF1 are found to have very similar structures.

==About this Structure==

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==Reference==

Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta ~~Crystallograph~~ Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17277441 17277441]

Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17277441 17277441]

[[Category: Rattus norvegicus]]

[[Category: Single protein]]

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[[Category: mitogen]]

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@@ Line 4: / Line 4: @@
 ==Overview==
-Fibroblast growth factors (FGFs) constitute a family of 22 structurally, related heparin-binding polypeptides that are involved in the regulation, of cell growth, survival, differentiation and migration. Here, a 1.4 A, resolution X-ray structure of rat FGF1 is presented. Two molecules are, present in the asymmetric unit of the crystal and they coordinate a total, of five sulfate ions. The structures of human, bovine and newt FGF1 have, been published previously. Human and rat FGF1 are found to have very, similar structures.
+Fibroblast growth factors (FGFs) constitute a family of 22 structurally related heparin-binding polypeptides that are involved in the regulation of cell growth, survival, differentiation and migration. Here, a 1.4 A resolution X-ray structure of rat FGF1 is presented. Two molecules are present in the asymmetric unit of the crystal and they coordinate a total of five sulfate ions. The structures of human, bovine and newt FGF1 have been published previously. Human and rat FGF1 are found to have very similar structures.
 ==About this Structure==
@@ Line 10: / Line 10: @@
 ==Reference==
-Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17277441 17277441]
+Structure of rat acidic fibroblast growth factor at 1.4 A resolution., Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):65-8. Epub 2007 Jan 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17277441 17277441]
 [[Category: Rattus norvegicus]]
 [[Category: Single protein]]
@@ Line 29: / Line 29: @@
 [[Category: mitogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb  3 10:41:12 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:58:50 2008''