Sandbox 666: Difference between revisions

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* Two arms, which establish contacts with DNA backbones outside the recognition sequences.
* Two arms, which establish contacts with DNA backbones outside the recognition sequences.


This binding by the major groove is due to the position of scissile phosphodiester bonds.
This binding by the major groove is due to the position of scissile phosphodiester bonds.<ref>Recognition and cleavage of DNA by type-II restriction endonucleases, Pingoud A. & Jeltsch A. Eur.J.Biochem. 246,1-22 (1997)</ref>


[[Image:Catalytic 1ERI.png | thumb | The catalytic core of Eco RI with the target DNA|left|400px]]
[[Image:Catalytic 1ERI.png | thumb | The catalytic core of Eco RI with the target DNA|left|400px]]