Sandbox 27: Difference between revisions

Revision as of 08:43, 30 December 2011 view source Nathalie Faggianelli (talk \| contribs) 187 edits →TSH and M22 ← Older edit		Revision as of 08:44, 30 December 2011 view source Nathalie Faggianelli (talk \| contribs) 187 edits →Signalling pathway Newer edit →
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	TSH hormone or in our case the autoantibody M22 binds to its receptor (more precisely to ~~the~~ LRD). This binding actives the receptor and then small G-proteins coupled to the receptor. The alpha subunit stimulates enzymes of the cellular membrane. A cascade of reactions and second messengers pathways are involved and result in the stimulation and the synthesis of thyroid hormones T3 and T4.		TSH hormone or in our case the autoantibody M22 binds to its receptor (more precisely to LRD). This binding actives the receptor and then small G-proteins coupled to the receptor. The alpha subunit stimulates enzymes of the cellular membrane. A cascade of reactions and second messengers pathways are involved and result in the stimulation and the synthesis of thyroid hormones T3 and T4.




	== Structure of the TSH Receptor ==		== Structure of the TSH Receptor ==

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