Sandbox 666: Difference between revisions
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The specific recognition of ''Eco''RI of the GAATTC sequence is mediated by twelve hydrogen bonds (six bonds per subunit) originating from α helical recognition modules. Three amino acids are responsible for the recognition:'''Arg<sup>200</sup>, Glu<sup>144</sup> and Arg<sup>145</sup>'''. These amino acids are shown in red <scene name='Sandbox_666/Grey_protein/3'>here</scene>. Each residue form two hydrogen bonds with Guanine and the adjacent Adenosine residues respectively. There are also two arms, which establish contacts with DNA backbones outside the recognition sequences. | The specific recognition of ''Eco''RI of the GAATTC sequence is mediated by twelve hydrogen bonds (six bonds per subunit) originating from α helical recognition modules. Three amino acids are responsible for the recognition: '''Arg<sup>200</sup>, Glu<sup>144</sup> and Arg<sup>145</sup>'''. These amino acids are shown in red <scene name='Sandbox_666/Grey_protein/3'>here</scene>. Each residue form two hydrogen bonds with Guanine and the adjacent Adenosine residues respectively. There are also two arms, which establish contacts with DNA backbones outside the recognition sequences. | ||
