Sandbox 213: Difference between revisions

=Mutation of Calmodulin gene and consequences=

Calmodulin is an essential protein and disruption of the single gene in yeast and fungi is lethal. However studies on Saccaromyces cerevisae had shown that Vertebrate calmodulin can rescue yeast cells whose calmodulin has been deleted. That experience indicates that Vertebrate calmodulin can functionally substitute for yeast calmodulin because Saccaromyces cerevisae has only one calmodulin gene (CMD1) that encodes for calmodulin which amino acids sequence is 60% identical to vertebrate Calmodulin.