Sandbox207: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Elise Rosati (talk | contribs) No edit summary |
Elise Rosati (talk | contribs) No edit summary |
||
| Line 22: | Line 22: | ||
===Gene structure, family=== | ===Gene structure, family=== | ||
:The CRP gene is located on chromosome 1q23. It is composed of two exons and one intron. This gene is regulated by interleukin-6, the principal inducer of the gene during the acute phase. CRP is secreted by hepatocytes.[http://www.rndsystems.com/cb_detail_objectname_SU05_CReactiveProtein.aspx] | :The CRP gene is located on chromosome 1q23. It is composed of two exons and one intron. This gene is regulated by interleukin-6, the principal inducer of the gene during the acute phase. CRP is secreted by hepatocytes.[http://www.rndsystems.com/cb_detail_objectname_SU05_CReactiveProtein.aspx <5>] | ||
:The Human CRP belongs to the pentraxin family of proteins having five identical, non-covalently associated subunits that form a symmetrical homopentameric ring. The pentraxin family is highly conserved in evolution.[http://www.jci.org/articles/view/18921 <3>] | :The Human CRP belongs to the pentraxin family of proteins having five identical, non-covalently associated subunits that form a symmetrical homopentameric ring. The pentraxin family is highly conserved in evolution.[http://www.jci.org/articles/view/18921 <3>] | ||
