Sandbox207: Difference between revisions
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::The C Reactive Protein is a protein of the '''acute phase''', the first described, exclusively synthetized by the liver. | ::The C Reactive Protein is a protein of the '''acute phase''', the first described, exclusively synthetized by the liver. | ||
The CRP was first isolated by '''Tillett and France in 1930''', in patients' serum presenting an acute inflammation. This protein reacted to the '''polysaccharide C''' of the pneumocoque, that is where its name comes from. [http://www.rndsystems.com/cb_detail_objectname_SU05_CReactiveProtein.aspx <1>] | :The CRP was first isolated by '''Tillett and France in 1930''', in patients' serum presenting an acute inflammation. This protein reacted to the '''polysaccharide C''' of the pneumocoque, that is where its name comes from. [http://www.rndsystems.com/cb_detail_objectname_SU05_CReactiveProtein.aspx <1>] | ||
:The CRP contributes to innate host defense, and plays an important role in inflammatory reactions. It can bind to specific molecular configurations typically exposed during cell death or found on the surfaces of pathogens. It is used as '''biological marker''' to reveal an inflammatory reaction and tissue damage. [http://biology.kenyon.edu/BMB/Chime2/2005/Jenny/FRAMES/ <2>] | ::The CRP contributes to innate host defense, and plays an important role in inflammatory reactions. It can bind to specific molecular configurations typically exposed during cell death or found on the surfaces of pathogens. It is used as '''biological marker''' to reveal an inflammatory reaction and tissue damage. [http://biology.kenyon.edu/BMB/Chime2/2005/Jenny/FRAMES/ <2>] | ||