Cytochrome P450: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Michal Harel (talk | contribs)
32,849 edits
No edit summary
Michal Harel (talk | contribs)
32,849 edits
No edit summary
Line 8: Line 8:
== 3D Structures of Cytochrome P450  ==
== 3D Structures of Cytochrome P450  ==


''Updated November 2011''
''Updated June 2012''


=== human P4501 family ===
=== human P450 1 family ===
   
   
[[2hi4]] – hP4501A2+naphthoflavone - human<br />
[[2hi4]] – hP4501A2+naphthoflavone - human<br />
[[3pm0]] - hP4501B1+naphthoflavone<br />
[[3pm0]] - hP4501B1+naphthoflavone<br />


=== human P4502 family ===
=== human P450 2 family ===
   
   
[[3gph]], [[3koh]], [[3lc4]] – hP4502E1 fragment +imidazole derivative<br />
[[2pg5]], [[2pg6]], [[2pg7]] – hP4502A6 (mutant)<br />
[[3e6i]] – hP4502E1 fragment+indazole<br />
[[3ebs]] – hP4502A6 (mutant)+phenacetin<br />
[[3ebs]] – hP4502A6 (mutant)+phenacetin<br />
[[2fdu]], [[2fdv]], [[2fdw]], [[2fdy]] - hP4502A6+pyridine derivative<br />
[[2fdu]], [[2fdv]], [[2fdw]], [[2fdy]] - hP4502A6+pyridine derivative<br />
[[1z10]] - hP4502A6 catalytic domain+coumarin<br />
[[1z10]] - hP4502A6 catalytic domain+coumarin<br />
[[3e4e]] – hP4502E1 fragment+methylpyrazole<br />
[[3t3q]], [[3t3r]] - hP4502A6 (mutant) + pilocarpine<br />
[[3czh]], [[3dl9]], [[3c6g]] – hP4502R1+vitamin D<br />
[[2z10]] – hP4502A6+coumarin<br />
[[1z11]] - hP4502A6+methoxalen<br />
[[3t3r]] - hP4502A13 + pilocarpine<br />
[[2p85]] – hP4502A13 (mutant)+indole<br />
[[3tk3]] - hP4502B4 (mutant) + imidazole derivative<br />
[[3ibd]] – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole<br />
[[2nnh]] – hP4502C8+retinoic acid<br />
[[2nnh]] – hP4502C8+retinoic acid<br />
[[2nni]] - hP4502C8+montelukast<br />
[[2nni]] - hP4502C8+montelukast<br />
Line 30: Line 34:
[[1og2]], [[1og5]] – hP4502C9 (mutant)<br />
[[1og2]], [[1og5]] – hP4502C9 (mutant)<br />
[[1r9o]] – hP4502C9 (mutant)+flurbiprofen<br />
[[1r9o]] – hP4502C9 (mutant)+flurbiprofen<br />
[[2pg5]], [[2pg6]], [[2pg7]] – hP4502A6 (mutant)<br />
[[2f9q]], [[3qm4]] – hP4502D6<br />
[[2p85]] – hP4502A13 (mutant)+indole<br />
[[3gph]], [[3koh]], [[3lc4]] – hP4502E1 fragment +imidazole derivative<br />  
[[3ibd]] – hP4502B6 (mutant)+4-(4-chlorophenyl)imidazole<br />
[[3e6i]] – hP4502E1 fragment+indazole<br />
[[2f9q]] – hP4502D6<br />
[[3e4e]] – hP4502E1 fragment+methylpyrazole<br />
[[2z10]] – hP4502A6+coumarin<br />
[[3t3z]] - hP4502E1 + pilocarpine<br />
[[1z11]] - hP4502A6+methoxalen
[[3czh]], [[3dl9]], [[3c6g]] – hP4502R1+vitamin D<br />
 


=== human P4503 family ===
=== human P450 3 family ===


[[2v0m]] – hP4503A4+ketoconazole<br />
[[2v0m]] – hP4503A4+ketoconazole<br />
[[2j0d]] - hP4503A4+erythromycin<br />
[[2j0d]] - hP4503A4+erythromycin<br />
[[3nxu]] - hP4503A4+ritonavir<br />
[[3nxu]], [[3tjs]] - hP4503A4+ritonavir<br />
[[3ua1]] - hP4503A4 + ergocryptine<br />
[[1tqn]], [[1w0e]], [[1w0f]], [[1w0g]] – hP4503A4<br />
[[1tqn]], [[1w0e]], [[1w0f]], [[1w0g]] – hP4503A4<br />




=== human P4507 family ===
=== human P450 7 family ===


[[3dax]] – hP4507A1<br />
[[3dax]] – hP4507A1<br />
[[3sn5]] - hP4507A1 + cholest-4-en-3-one
[[3sn5]] - hP4507A1 + cholest-4-en-3-one


=== human P45019 family ===
=== human P450 19 family ===


[[3eqm]] - hP45019A1+androstenedione
[[3eqm]] - hP45019A1+androstenedione




=== human P45046 family ===
=== human P450 46 family ===


[[2q9f]] – hP45046A1+cholesterol<br />
[[2q9f]] – hP45046A1+cholesterol<br />
Line 202: Line 206:
[[3dsk]] - AtP45074A (mutant)+ vernolic acid<br />
[[3dsk]] - AtP45074A (mutant)+ vernolic acid<br />
[[2rcm]], [[3cli]] - AtP45074A<br />
[[2rcm]], [[3cli]] - AtP45074A<br />
[[3r9b]] – MsP45016A2 – ''Mycobacterium smegmatis''<br />
[[3r9c]] – MsP45016A2 + econazole<br />
[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
[[2rfb]] – PtP450 – ''Picrophilus torridus''<br />
[[2rfc]] – PtP450+phenylimidazole<br />
[[2rfc]] – PtP450+phenylimidazole<br />
Line 210: Line 216:
[[3lxh]], [[3lxi]], [[3ofu]] – NaP240101D1 – ''Novosphingobium aromaticivorans''<br />
[[3lxh]], [[3lxi]], [[3ofu]] – NaP240101D1 – ''Novosphingobium aromaticivorans''<br />
[[3nv5]], [[3nv6]] - NaP240101D2<br />
[[3nv5]], [[3nv6]] - NaP240101D2<br />
[[3tkt]] – NaP450108D1<br />
[[3awm]] – SpP450-α + palmitic acid – ''Sphingomonas paucimobilis''<br />
[[3awm]] – SpP450-α + palmitic acid – ''Sphingomonas paucimobilis''<br />
[[3awp]], [[3awq]] - SpP450-α (mutant)<br />
[[3awp]], [[3awq]] - SpP450-α (mutant)<br />
Retrieved from "https://proteopedia.org/Cytochrome_P450"