3s5b: Difference between revisions

Revision as of 09:12, 19 June 2013

[NUCG_CAEEL] Endonuclease important for programmed cell death; it mediates apoptotic DNA fragmentation.

3s5b is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Lin JL, Nakagawa A, Lin CL, Hsiao YY, Yang WZ, Wang YT, Doudeva LG, Skeen-Gaar RR, Xue D, Yuan HS. Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans. J Biol Chem. 2012 Mar 2;287(10):7110-20. Epub 2012 Jan 5. PMID:22223640 doi:10.1074/jbc.M111.316075

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-[[Image:3s5b.png|left|200px]]
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 {{STRUCTURE_3s5b|  PDB=3s5b  |  SCENE=  }}
 ===Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans===
+{{ABSTRACT_PUBMED_22223640}}
+==Function==
+[[http://www.uniprot.org/uniprot/NUCG_CAEEL NUCG_CAEEL]] Endonuclease important for programmed cell death; it mediates apoptotic DNA fragmentation.
 ==About this Structure==
 [[3s5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5B OCA].
+==Reference==
+<ref group="xtra">PMID:022223640</ref><references group="xtra"/><references/>
 [[Category: Caenorhabditis elegans]]
 [[Category: Lin, J L.J.]]