3cxw: Difference between revisions
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Revision as of 10:05, 18 January 2012
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I
Template:ABSTRACT PUBMED 22136433
About this Structure
3cxw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. 7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes. J Med Chem. 2012 Jan 12;55(1):403-13. Epub 2012 Jan 3. PMID:22136433 doi:10.1021/jm201286z
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Arrowsmith, C H.
- Bountra, C.
- Bracher, F.
- Bullock, A.
- Delft, F von.
- Edwards, A M.
- Fedorov, O.
- Filippakopoulos, P.
- Huber, K.
- Knapp, S.
- Pike, A C.W.
- Roos, A.
- SGC, Structural Genomics Consortium.
- Alternative initiation
- Atp-binding
- Host-virus interaction
- Kinase
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Nucleus
- Oncogene
- Phosphoprotein
- Pim1
- Proto-oncogene
- Serine-threonine
- Serine/threonine-protein kinase
- Sgc
- Structural genomics consortium
- Transferase
- Viral immunoevasion
- Virion
- Virulence
