4agn: Difference between revisions
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===Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5116=== | |||
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{{ABSTRACT_PUBMED_17015838}} | |||
==About this Structure== | |||
[[4agn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGN OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:017015838</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Boeckler, F M.]] | |||
[[Category: Fersht, A R.]] | |||
[[Category: Joerger, A C.]] | |||
[[Category: Wilcken, R.]] | |||
[[Category: Acetylene linker]] | |||
[[Category: Apoptosis]] | |||
[[Category: Cancer mutation]] | |||
[[Category: Cell cycle]] | |||
[[Category: Halogen bonding]] | |||
[[Category: Protein stabilization]] | |||
[[Category: Small-molecule drug]] | |||
[[Category: Surface crevice]] | |||
[[Category: Transcription]] | |||
[[Category: Zinc binding]] | |||
Revision as of 07:51, 21 March 2012
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5116
Template:ABSTRACT PUBMED 17015838
About this Structure
4agn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838
