4dfg: Difference between revisions
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===Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A=== | |||
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{{ABSTRACT_PUBMED_22364812}} | |||
==About this Structure== | |||
[[4dfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFG OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022364812</ref><references group="xtra"/> | |||
[[Category: HIV-1 retropepsin]] | |||
[[Category: Human immunodeficiency virus 1]] | |||
[[Category: Agniswamy, J.]] | |||
[[Category: Wang, Y F.]] | |||
[[Category: Weber, I T.]] | |||
[[Category: Aspartic acid protease]] | |||
[[Category: Cyclopentyltetrahydro- furanyl urethanes p2-ligand]] | |||
[[Category: Hiv-1 protease inhibitor grl-0249a]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Wild-type hiv-1 protease]] | |||
Revision as of 07:34, 21 March 2012
Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A
Template:ABSTRACT PUBMED 22364812
About this Structure
4dfg is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Ghosh AK, Chapsal BD, Steffey M, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2308-11. Epub 2012 Feb 2. PMID:22364812 doi:10.1016/j.bmcl.2012.01.061
