4a5s: Difference between revisions
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[[Image:4a5s. | [[Image:4a5s.png|left|200px]] | ||
{{STRUCTURE_4a5s| PDB=4a5s | SCENE= }} | {{STRUCTURE_4a5s| PDB=4a5s | SCENE= }} | ||
===CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR=== | ===CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR=== | ||
{{ABSTRACT_PUBMED_22177783}} | {{ABSTRACT_PUBMED_22177783}} | ||
==About this Structure== | ==About this Structure== | ||
[[4a5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A5S OCA]. | [[4a5s]] is a 2 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A5S OCA]. | ||
==See Also== | |||
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | |||
==Reference== | ==Reference== | ||
Revision as of 18:45, 26 July 2012
CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR
Template:ABSTRACT PUBMED 22177783
About this Structure
4a5s is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sutton JM, Clark DE, Dunsdon SJ, Fenton G, Fillmore A, Harris NV, Higgs C, Hurley CA, Krintel SL, Mackenzie RE, Duttaroy A, Gangl E, Maniara W, Sedrani R, Namoto K, Ostermann N, Gerhartz B, Sirockin F, Trappe J, Hassiepen U, Baeschlin DK. Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1464-8. Epub 2011 Nov 20. PMID:22177783 doi:10.1016/j.bmcl.2011.11.054
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Categories:
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- Dipeptidyl-peptidase IV
- Homo sapiens
- Baeschlin, D K.
- Clark, D E.
- Dunsdon, S J.
- Duttaroy, A.
- Fenton, G.
- Fillmore, A.
- Gangl, E.
- Gerhartz, B.
- Harris, N V.
- Hassiepen, U.
- Higgs, C.
- Hurley, C A.
- Krintel, S L.
- Kroemer, M.
- Mackenzie, R E.
- Maniara, W.
- Namoto, K.
- Ostermann, N.
- Sedrani, R.
- Sirockin, F.
- Sutton, J M.
- Trappe, J.
- Zink, F.
- Hydrolase
- Novartis compound nvp-biv988
- Type 2 diabetes