2q1l: Difference between revisions

Revision as of 06:24, 27 July 2012

2q1l is a 4 chain structure of HMG-CoA Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Pfefferkorn JA, Song Y, Sun KL, Miller SR, Trivedi BK, Choi C, Sorenson RJ, Bratton LD, Unangst PC, Larsen SD, Poel TJ, Cheng XM, Lee C, Erasga N, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu G, Robertson A, Olsen K, Mertz T, Sekerke C, Pavlovsky A, Harris MS, Bainbridge G, Caspers N, Chen H, Eberstadt M. Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4538-44. Epub 2007 Jun 6. PMID:17574412 doi:10.1016/j.bmcl.2007.05.096

@@ Line 1: / Line 1: @@
 [[Image:2q1l.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_2q1l", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_2q1l|  PDB=2q1l  |  SCENE=  }}
 ===Design and Synthesis of Pyrrole-based, Hepatoselective HMG-CoA Reductase Inhibitors===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_17574412}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 17574412 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_17574412}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[HMG-CoA Reductase]]
+*[[HMG-CoA Reductase|HMG-CoA Reductase]]
 ==Reference==