T-box proteins: Difference between revisions
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=Introduction= | =Introduction= | ||
The family of T-box proteins are transcription factors with a transcriptional activator or repressor domain and a DNA-binding T-box domain. The first two proteins discovered were Brachyury and Omb, which were found to have a new distinct domain unlike any other, designated the T-box domain. Other homologous proteins have been discovered in both invertebrate and vertebrate organisms but not in some organisms such as ''Aribidopsis thaliana''. This family has ~20 members in ''Homo sapiens''. | The family of T-box proteins are transcription factors with a transcriptional activator or repressor domain and a DNA-binding T-box domain. The first two proteins discovered were Brachyury and Omb, which were found to have a new distinct domain unlike any other, designated the T-box domain. Other homologous proteins have been discovered in both invertebrate and vertebrate organisms but not in some organisms such as ''Aribidopsis thaliana''. This family has ~20 members in ''Homo sapiens''. For details see [[TBX3}}. | ||
=Gene loci and structure= | =Gene loci and structure= | ||
