TolR: Difference between revisions
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==Structure== | ==Structure== | ||
'''TolR''' is a bitopic protein located in the inner membrane and consists of three domains: domain I (from residues 1 to 43 and including the transmembrane domain between residues 23 to 43), domain II and domain III from residues 117 to 142<ref name='Journet'>PMID: 10419942</ref>. Domains II and III have the ability to dimerize, but unlike domains I and III, domain II is poorly conserved<ref>PMID: 11994151</ref>. | '''TolR''' is a bitopic protein located in the inner membrane and consists of three domains: domain I (from residues 1 to 43 and including the transmembrane domain between residues 23 to 43), domain II and domain III from residues 117 to 142<ref name='Journet'>PMID: 10419942</ref>. Domains II and III have the ability to dimerize, but unlike domains I and III, domain II is poorly conserved<ref>PMID: 11994151</ref>. For additional details see [[Tol]]. | ||
Domain III has been suggested to form an amphiphilic α-helix, which play an essential role in the functional assembly of the [[Tol]] complex<ref name='Lazzaroni'>PMID: 7853390</ref>. | Domain III has been suggested to form an amphiphilic α-helix, which play an essential role in the functional assembly of the [[Tol]] complex<ref name='Lazzaroni'>PMID: 7853390</ref>. | ||
