3vjm: Difference between revisions

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'''Unreleased structure'''
[[Image:3vjm.jpg|left|200px]]


The entry 3vjm is ON HOLD until Paper Publication
{{STRUCTURE_3vjm|  PDB=3vjm  |  SCENE=  }}


Authors: Akahoshi, F., Kishida, H., Miyaguchi, I., Yoshida, T., Ishii, S.
===Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1===


Description: Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1
{{ABSTRACT_PUBMED_22824762}}
 
==About this Structure==
[[3vjm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VJM OCA].
 
==Reference==
<ref group="xtra">PMID:022824762</ref><references group="xtra"/>
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Homo sapiens]]
[[Category: Akahoshi, F.]]
[[Category: Ishii, S.]]
[[Category: Kishida, H.]]
[[Category: Miyaguchi, I.]]
[[Category: Yoshida, T.]]
[[Category: Alpha/beta]]
[[Category: Aminopeptidase]]
[[Category: Beta-propeller]]
[[Category: Cell membrane]]
[[Category: Diabetes]]
[[Category: Glycoprotein]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Serine protease]]
[[Category: Signal-anchor]]
[[Category: Transmembrane]]

Revision as of 05:46, 15 August 2012

File:3vjm.jpg

Template:STRUCTURE 3vjm

Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1

Template:ABSTRACT PUBMED 22824762

About this Structure

3vjm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Yoshida T, Akahoshi F, Sakashita H, Sonda S, Takeuchi M, Tanaka Y, Nabeno M, Kishida H, Miyaguchi I, Hayashi Y. Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group. Bioorg Med Chem. 2012 Aug 15;20(16):5033-41. Epub 2012 Jul 5. PMID:22824762 doi:10.1016/j.bmc.2012.06.033

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