Ubiquitin chains: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 51: Line 51:


== Chains of Ubiquitin-like proteins (Ubls) ==
== Chains of Ubiquitin-like proteins (Ubls) ==
<Structure load='1z2m' size='300' frame='true' align='right' caption='Structure of a ISG15 monomer. The tertiary structure consists of two ubiquitin-like folds, resembling a molecule of diubiquitin.' scene='Insert optional scene name here' />
<Structure load='1z2m' size='300' frame='true' align='right' caption='Structure of a ISG15 monomer. The tertiary structure consists of two ubiquitin-like folds, resembling a molecule of diubiquitin, [[1z2m]].' scene='Insert optional scene name here' />
SUMO (Small Ubiquitin-like Modifying Object) does form chains<ref>PMID: 11451954</ref>, however no structural information on these chains is available. Chains of other Ubls may exist, but there is not significant data on their structure and function. The tertiary structure of ISG15 is comprised of two beta grasp folds and is similar in appearance to diubiquitin <ref>PMID: 15917233</ref>. Whether this influences the function of ISG15 is not clear at this time.  
SUMO (Small Ubiquitin-like Modifying Object) does form chains<ref>PMID: 11451954</ref>, however no structural information on these chains is available. Chains of other Ubls may exist, but there is not significant data on their structure and function. The tertiary structure of ISG15 is comprised of two beta grasp folds and is similar in appearance to diubiquitin <ref>PMID: 15917233</ref>. Whether this influences the function of ISG15 is not clear at this time.