3nps: Difference between revisions

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[[Image:3nps.png|left|200px]]
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===Crystal structure of membrane-type serine protease 1 (MT-SP1) in complex with the Fab Inhibitor S4===
===Crystal structure of membrane-type serine protease 1 (MT-SP1) in complex with the Fab Inhibitor S4===
{{ABSTRACT_PUBMED_22154938}}


==Disease==
[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:[http://omim.org/entry/610765 610765]]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.<ref>PMID:17273967</ref>


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_22154938}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/ST14_HUMAN ST14_HUMAN]] Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.  
(as it appears on PubMed at http://www.pubmed.gov), where 22154938 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22154938}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:022154938</ref><references group="xtra"/>
<ref group="xtra">PMID:022154938</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Matriptase]]
[[Category: Matriptase]]