4dem: Difference between revisions
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[[Image:4dem.jpg|left|200px]] | |||
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{{STRUCTURE_4dem| PDB=4dem | SCENE= }} | |||
===Crystal structure of human FPPS in complex with YS_04_70=== | |||
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{{ABSTRACT_PUBMED_22390415}} | |||
==About this Structure== | |||
[[4dem]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022390415</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Berghuis, A M.]] | |||
[[Category: Lin, Y S.]] | |||
[[Category: Park, J.]] | |||
[[Category: Tsantrizos, Y S.]] | |||
[[Category: Bisphosphonate]] | |||
[[Category: Cholesterol biosynthesis]] | |||
[[Category: Isoprene biosynthesis]] | |||
[[Category: Mevalonate pathway]] | |||
[[Category: Transferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 07:37, 21 March 2012
Crystal structure of human FPPS in complex with YS_04_70
Template:ABSTRACT PUBMED 22390415
About this Structure
4dem is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lin YS, Park J, De Schutter JW, Huang XF, Berghuis AM, Sebag M, Tsantrizos YS. Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J Med Chem. 2012 Mar 19. PMID:22390415 doi:10.1021/jm201657x
