4drk: Difference between revisions
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[[Image:4drk.jpg|left|200px]] | |||
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===EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid=== | |||
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{{ABSTRACT_PUBMED_22455444}} | |||
==About this Structure== | |||
[[4drk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DRK OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022455444</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Peptidylprolyl isomerase]] | |||
[[Category: Bracher, A.]] | |||
[[Category: Gaali, S.]] | |||
[[Category: Gopalakrishnan, R.]] | |||
[[Category: Hausch, F.]] | |||
[[Category: Hoogeland, B.]] | |||
[[Category: Kozany, C.]] | |||
[[Category: Kress, C.]] | |||
[[Category: Fk-506 binding domain]] | |||
[[Category: Hsp90 cochaperone]] | |||
[[Category: Immunophilin]] | |||
[[Category: Isomerase]] | |||
[[Category: Peptidyl-prolyl isomerase]] | |||
Revision as of 09:14, 16 May 2012
EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR FKBP51 AND FKBP52: COMPLEX OF FKBP51 WITH {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
Template:ABSTRACT PUBMED 22455444
About this Structure
4drk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gopalakrishnan R, Kozany C, Gaali S, Kress C, Hoogeland B, Bracher A, Hausch F. Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52. J Med Chem. 2012 May 10;55(9):4114-22. Epub 2012 Apr 19. PMID:22455444 doi:10.1021/jm201746x
