Catalase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_1gge| PDB=1gge | SIZE=400| SCENE= |right|CAPTION=E. coli catalase Hpii showing the heme group, [[1gge]] }} | {{STRUCTURE_1gge| PDB=1gge | SIZE=400| SCENE= |right|CAPTION=E. coli catalase Hpii showing the heme group, [[1gge]] }} | ||
'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). CAT KatG is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). | '''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). | ||
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
