3p11: Difference between revisions

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~~[[Image:3p11.png|left|200px]]~~

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~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~

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===anti-EGFR/HER3 Fab DL11 in complex with domains I-III of the HER3 extracellular region===

==Disease==

[[http://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN]] Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2) [MIM:[http://omim.org/entry/607598 607598]]; also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord. The LCCS2 syndrome is characterized by multiple joint contractures, anterior horn atrophy in the spinal cord, and a unique feature of a markedly distended urinary bladder. The phenotype suggests a spinal cord neuropathic etiology.<ref>PMID:17701904</ref>

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==Function==

~~The line below this paragraph, {{ABSTRACT_PUBMED_22014573}}, adds the Publication Abstract to the page~~

[[http://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN]] Binds and is activated by neuregulins and NTAK.<ref>PMID:15358134</ref>

~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 22014573~~ is ~~the PubMed ID number~~.

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~~{{ABSTRACT_PUBMED_22014573}}~~

==About this Structure==

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==Reference==

[[Category: Homo sapiens]]

[[Category: Receptor protein-tyrosine kinase]]

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@@ Line 1: / Line 1: @@
-[[Image:3p11.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3p11", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3p11|  PDB=3p11  |  SCENE=  }}
 ===anti-EGFR/HER3 Fab DL11 in complex with domains I-III of the HER3 extracellular region===
+{{ABSTRACT_PUBMED_22014573}}
+==Disease==
+[[http://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN]] Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2) [MIM:[http://omim.org/entry/607598 607598]]; also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord. The LCCS2 syndrome is characterized by multiple joint contractures, anterior horn atrophy in the spinal cord, and a unique feature of a markedly distended urinary bladder. The phenotype suggests a spinal cord neuropathic etiology.<ref>PMID:17701904</ref>
-<!--
+==Function==
-The line below this paragraph, {{ABSTRACT_PUBMED_22014573}}, adds the Publication Abstract to the page
+[[http://www.uniprot.org/uniprot/ERBB3_HUMAN ERBB3_HUMAN]] Binds and is activated by neuregulins and NTAK.<ref>PMID:15358134</ref>
-(as it appears on PubMed at http://www.pubmed.gov), where 22014573 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_22014573}}
 ==About this Structure==
@@ Line 22: / Line 13: @@
 ==Reference==
-<ref group="xtra">PMID:022014573</ref><references group="xtra"/>
+<ref group="xtra">PMID:022014573</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Receptor protein-tyrosine kinase]]