2yge: Difference between revisions

Revision as of 13:10, 6 February 2013

2yge is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. FASEB J. 2011 Nov;25(11):3828-37. Epub 2011 Jul 21. PMID:21778327 doi:10.1096/fj.11-188821

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 [[Image:2yge.png|left|200px]]
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 ===E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin===
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