1ftn: Difference between revisions
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==Overview== | ==Overview== | ||
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses | RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Derewenda, U.]] | [[Category: Derewenda, U.]] | ||
[[Category: Derewenda, Z | [[Category: Derewenda, Z S.]] | ||
[[Category: Liu, X.]] | [[Category: Liu, X.]] | ||
[[Category: Minor, W.]] | [[Category: Minor, W.]] | ||
[[Category: Nakamoto, R | [[Category: Nakamoto, R K.]] | ||
[[Category: Somlyo, A | [[Category: Somlyo, A P.]] | ||
[[Category: Somlyo, A | [[Category: Somlyo, A V.]] | ||
[[Category: Wei, Y.]] | [[Category: Wei, Y.]] | ||
[[Category: Zhang, Y.]] | [[Category: Zhang, Y.]] | ||
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[[Category: small p-protein]] | [[Category: small p-protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:42:31 2008'' | ||
Revision as of 10:42, 21 February 2008
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CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Overview
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.
About this Structure
1FTN is a Single protein structure of sequence from Homo sapiens with MG and GDP as ligands. Full crystallographic information is available from OCA.
Reference
Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995
Page seeded by OCA on Thu Feb 21 12:42:31 2008
