3uzy: Difference between revisions

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[[Image:3uzy.jpg|left|200px]]
[[Image:3uzy.png|left|200px]]


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{{STRUCTURE_3uzy|  PDB=3uzy  |  SCENE=  }}  
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===Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and 5beta-dihydrotestosterone===
===Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and 5beta-dihydrotestosterone===


{{ABSTRACT_PUBMED_22437839}}


==About this Structure==
==About this Structure==
[[3uzy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZY OCA].  
[[3uzy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZY OCA].  
==Reference==
<ref group="xtra">PMID:022437839</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chen, M.]]
[[Category: Chen, M.]]

Revision as of 04:36, 27 June 2012

File:3uzy.png

Template:STRUCTURE 3uzy

Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and 5beta-dihydrotestosterone

Template:ABSTRACT PUBMED 22437839

About this Structure

3uzy is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chen M, Drury JE, Christianson DW, Penning TM. Conversion of human steroid 5beta-reductase (AKR1D1) into 3beta-hydroxysteroid dehydrogenase by single point mutation E120H: example of perfect enzyme engineering. J Biol Chem. 2012 May 11;287(20):16609-22. Epub 2012 Mar 20. PMID:22437839 doi:10.1074/jbc.M111.338780

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