3rix: Difference between revisions

Revision as of 09:41, 5 December 2012

3rix is a 1 chain structure with sequence from Photinus pyralis. Full crystallographic information is available from OCA.

Cruz PG, Auld DS, Schultz PJ, Lovell S, Battaile KP, MacArthur R, Shen M, Tamayo-Castillo G, Inglese J, Sherman DH. Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors. Chem Biol. 2011 Nov 23;18(11):1442-52. PMID:22118678 doi:10.1016/j.chembiol.2011.08.011

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 [[Image:3rix.png|left|200px]]
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 ===1.7A resolution structure of a firefly luciferase-Aspulvinone J inhibitor complex===
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