2lm2: Difference between revisions

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[[Image:2lm2.jpg|left|200px]]
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{{STRUCTURE_2lm2|  PDB=2lm2  |  SCENE=  }}  
{{STRUCTURE_2lm2|  PDB=2lm2  |  SCENE=  }}  
===NMR structures of the transmembrane domains of the AChR b2 subunit===
===NMR structures of the transmembrane domains of the AChR b2 subunit===
{{ABSTRACT_PUBMED_22361591}}


==Disease==
[[http://www.uniprot.org/uniprot/ACHB2_HUMAN ACHB2_HUMAN]] Defects in CHRNB2 are the cause of nocturnal frontal lobe epilepsy type 3 (ENFL3) [MIM:[http://omim.org/entry/605375 605375]]. ENFL3 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.<ref>PMID:11062464</ref><ref>PMID:11104662</ref>


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_22361591}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/ACHB2_HUMAN ACHB2_HUMAN]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.<ref>PMID:22361591</ref>  
(as it appears on PubMed at http://www.pubmed.gov), where 22361591 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22361591}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:022361591</ref><references group="xtra"/>
<ref group="xtra">PMID:022361591</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bondarenko, V.]]
[[Category: Bondarenko, V.]]