Nitroreductase: Difference between revisions
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'''Nitroreductase''' (NR) is involved in the reduction of nitrogen-containing compounds including those containing | '''Nitroreductase''' (NR) is involved in the reduction of nitrogen-containing compounds including those containing NO<sup>2</sup> group. The NO<sup>2</sup> group is reduced to hydroxylamine. NR use FMN as cofactor. Among NRs are the oxygen-insensitive NAD(P)H NR and NADH dehydrogenase. The NR is of special interest due to its potential use as activator of prodrugs in cancer therapy. | ||
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==3D structures of nitroreductase== | ==3D structures of nitroreductase== | ||
