Sandbox Reserved 489: Difference between revisions
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Renin is important clinically because renin inhibitors, such as [http://en.wikipedia.org/wiki/Aliskiren Aliskiren] can be used to treat hypertension. | Renin is important clinically because renin inhibitors, such as [http://en.wikipedia.org/wiki/Aliskiren Aliskiren] can be used to treat hypertension. | ||
==Structure== | |||
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<Structure load='2ren' size='400' frame='true' align='right' caption='Mature Renin' scene='Insert optional scene name here' /> | <Structure load='2ren' size='400' frame='true' align='right' caption='Mature Renin' scene='Insert optional scene name here' /> | ||
The precursor of renin is a 406 amino acid residue protein. <scene name='Sandbox_Reserved_489/Signal_domain/1'>Residues 1-23</scene> are a signal peptide sequence and residues 24-66 are cleaved to produce the mature 340 amino acid residue <scene name='Sandbox_Reserved_489/Mature_renin/1'>mature renin</scene>. | The precursor of renin is a 406 amino acid residue protein. <scene name='Sandbox_Reserved_489/Signal_domain/1'>Residues 1-23</scene> are a signal peptide sequence and residues 24-66 are cleaved to produce the mature 340 amino acid residue <scene name='Sandbox_Reserved_489/Mature_renin/1'>mature renin</scene>. | ||