3v00: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3v00| PDB=3v00 | SCENE= }} | {{STRUCTURE_3v00| PDB=3v00 | SCENE= }} | ||
===Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.=== | ===Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.=== | ||
{{ABSTRACT_PUBMED_22448927}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GNAT1_BOVIN GNAT1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. | |||
==About this Structure== | ==About this Structure== | ||
[[3v00]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus | [[3v00]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V00 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022448927</ref><references group="xtra"/> | <ref group="xtra">PMID:022448927</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus | [[Category: Bos taurus]] | ||
[[Category: Cerione, R A.]] | [[Category: Cerione, R A.]] | ||
[[Category: Singh, G.]] | [[Category: Singh, G.]] | ||
Revision as of 07:04, 30 June 2013
Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.
Template:ABSTRACT PUBMED 22448927
Function
[GNAT1_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
About this Structure
3v00 is a 3 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Singh G, Ramachandran S, Cerione RA. A constitutively active galpha subunit provides insights into the mechanism of g protein activation. Biochemistry. 2012 Apr 17;51(15):3232-40. Epub 2012 Apr 5. PMID:22448927 doi:10.1021/bi3001984