Sandbox Reserved 466: Difference between revisions
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== Introduction == | == Introduction == | ||
The tetanus toxin, or ''Clostridium tetani'', is produced by the bacteria Clostridium. Clostridium bacteria produces distinct neurotoxins that are extremely potent to humans. It releases two types of neurotoxins: | The tetanus toxin, or ''Clostridium tetani'', is produced by the bacteria Clostridium. Clostridium bacteria produces distinct neurotoxins that are extremely potent to humans. It releases two types of neurotoxins: ''Clostridium botulinum'' and ''Clostridium tetani''. It is part of the peptidase M27 family of proteins, which are metalloproteases. Metalloproteases bind with a divalent cation, usually zinc, which activates water molecules within the active site to hydrolyze peptide bonds. | ||
Clostridium tetani | Clostridium tetani functions by inhibiting neurotransmitter release into the synaptic cleft of the spinal cord. It mimics a zinc peptidase | ||
