Sandbox Reserved 468: Difference between revisions
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There is not a generally accepted mechanism of action for this enzyme but there are three possible catalytic mechanisms published. Note that all of these mechanisms somehow involve the zinc ion, which is found in the catalytic domain and believed to play an important role in catalysis. | There is not a generally accepted mechanism of action for this enzyme but there are three possible catalytic mechanisms published. Note that all of these mechanisms somehow involve the zinc ion, which is found in the catalytic domain and believed to play an important role in catalysis. | ||
Taken from a publication of the crystal structure. | |||
[[Image:mmp_active.jpg]] | |||
In the first mechanism, Browner M.F. and colleagues proposed the base-catalysis mechanism, carried out by the conserved glutamate residue and the Zn2+ ion [5][6]. | In the first mechanism, Browner M.F. and colleagues proposed the base-catalysis mechanism, carried out by the conserved glutamate residue and the Zn2+ ion [5][6]. | ||
