Sandbox Reserved 477: Difference between revisions
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<Structure load='1VC2' size='500' frame='true' align='right' caption='This is Glyceraldehyde-3-Phosphate Dehydrogenase isolated from Thermus thermophilus HB8' scene='Insert optional scene name here' /> | <Structure load='1VC2' size='500' frame='true' align='right' caption='This is Glyceraldehyde-3-Phosphate Dehydrogenase isolated from Thermus thermophilus HB8' scene='Insert optional scene name here' /> | ||
Structure | Structure | ||
<scene name='Sandbox_Reserved_477/Ligand/1'>Ligand</scene> | |||
Diseases | Diseases | ||
Glyceraldehyde-3-Phosphate Dehydrogenase deficiency is a rare genetic disorder in which an individual has a deficiency of GAPDH, which is heavily involved in breaking down carbohydrates consumed in the diet in order to produce energy. This condition is asymptomatic and affects less than 200,000 people in the United States. GAPDH deficiency also occurs in plants, known as plastidial GAPDH deficiency. In plants, glycolysis occurs in both the cytosol and plastids. In a chloroplast/plastid-localized GAPDH isoform, gapcp, these double mutants have produced drastic phenotypes of arrested root development, dwarfism, and sterility. | Glyceraldehyde-3-Phosphate Dehydrogenase deficiency is a rare genetic disorder in which an individual has a deficiency of GAPDH, which is heavily involved in breaking down carbohydrates consumed in the diet in order to produce energy. This condition is asymptomatic and affects less than 200,000 people in the United States. GAPDH deficiency also occurs in plants, known as plastidial GAPDH deficiency. In plants, glycolysis occurs in both the cytosol and plastids. In a chloroplast/plastid-localized GAPDH isoform, gapcp, these double mutants have produced drastic phenotypes of arrested root development, dwarfism, and sterility. | ||
